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Variability of nutrients intake, lipid profile and cardiovascular mortality among geographical areas in Spain: The DRECE study

Agustín Gómez de la Cámara, Eva de Andrés Esteban, Gerard Urrútia Cuchí, Enrique Calderón Sandubete, Miguel Ángel Rubio Herrera, Miguel Menéndez Orenga, David Lora Pablos
  • Agustín Gómez de la Cámara
    Instituto de Investigación Hospital 12 de Octubre, Madrid; CIBER Epidemiología y Salud Pública, Madrid, Spain | acamara@h12o.es
  • Eva de Andrés Esteban
    Instituto de Investigación Hospital 12 de Octubre, Madrid; CIBER Epidemiología y Salud Pública, Madrid, Spain
  • Gerard Urrútia Cuchí
    CIBER Epidemiología y Salud Pública, Madrid; Hospital Santa Creu i Sant Pau, Barcelona, Spain
  • Enrique Calderón Sandubete
    CIBER Epidemiología y Salud Pública, Madrid; Hospital Virgen del Rocio, Sevilla, Spain
  • Miguel Ángel Rubio Herrera
    Servicio de Endocrinología y Nutrición, Hospital Clínico Universitario de San Carlos, Madrid, Spain
  • Miguel Menéndez Orenga
    Instituto de Investigación Hospital 12 de Octubre, Madrid, Spain
  • David Lora Pablos
    Instituto de Investigación Hospital 12 de Octubre, Madrid; CIBER Epidemiología y Salud Pública, Madrid, Spain

Abstract

It has often been suggested that cardiovascular mortality and their geographical heterogeneity are associated with nutrients intake patterns and also lipid profile. The large Spanish study Dieta y Riesgo de Enfermedades Cardiovasculares en España (DRECE) investigated this theory from 1991 to 2010. Out of the 4,783 Spanish individuals making up the DRECE cohort, 220 subjects (148 men and 72 women) died (4.62%) during the course of the study. The mean age of patients who died from cardiovascular causes (32 in all) was 61.08 years 95% CI (57.47-64.69) and 70.91% of them were males. The consumption of nutrients and the lipid profile by geographical area, studied by geospatial models, showed that the east and southern area of the country had the highest fat intake coupled to a high rate of unhealthy lipid profile. It was concluded that the spatial geographical analysis showed a relationship between high fat intake, unhealthy lipid profile and cardiovascular mortality in the different geographical areas, with a high variability within the country.

Keywords

Cardiovascular mortality; Geographic variability; Lipid profile; Spatial analysis; Spain

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Submitted: 2016-10-13 10:36:04
Published: 2017-11-07 10:38:30
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