Original Articles
12 September 2025
Vol. 20 No. 2 (2025)
Lung cancer associated with natural vegetation cover: spatial analysis in the state of Pará, eastern Brazil
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All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
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Lung cancer represents the second-highest incidence of cancer worldwide and the leading cause of cancer-related deaths. Smoking is still the main risk factor, but other factors are also important, such as those associated with the large-scale exploitation of natural resources. This ecological study aimed to analyse the potential association between the spatial distribution of lung cancer and the natural vegetation cover in the state of Pará, Brazil. The study included 700 new cases of lung cancer taken from the Integrador Hospital Cancer Registries, a web-based system consolidating cancer data across Brazil. Spatial exploratory techniques were estimated by global and local spatial correlation coefficients and presented as thematic maps. The independent variables were socio-economic and environmental indicators. A significant variation was identified between different geographical areas and the distribution pattern of lung cancer incidence, with a negative correlation (I = - 0.12, p-value = < 0.001) between cancer rates and natural vegetation cover. The findings provide insights into the role of environmental factors that influence public health, ratifying the need for environmental conservation policies to promote health and prevent disease.
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Citations
Aceng FL, Kabwama SN, Ario AR, Etwom A, Turyahabwe S, Mugabe FR, 2024. Spatial distribution and temporal trends of tuberculosis case notifications, Uganda: a ten-year retrospective analysis (2013-2022). BMC Infect Dis 24:46. DOI: https://doi.org/10.1186/s12879-023-08951-0
Amorim IA, Homma AK, 2022. Landscape change in the southeastern mesoregion of Pará: coevolution with cattle ranching and settlement projects. Bol Geogr (Online) 40:186-206. DOI: https://doi.org/10.4025/bolgeogr.v40.a2022.e62277
Araújo RA, Barbosa Júnior IO, Santos GG, 2023. The advance of the agricultural frontier in the eastern Amazon: an analysis of land use and land cover in the soya producing municipalities of the Paragominas-PA micro-region. Cad Geogr 33:658-688. DOI: https://doi.org/10.5752/P.2318-2962.2023v33n73p658
Arcêncio RA, Belchior AS, Arroyo LH, Bruce ATI, Santos FL, Yamamura M, Queiroz AAR, Santos DT, Uchôa SAC, Nunes C, 2022. Spatial distribution and dependence of mortality due to tuberculosis in a city in the Amazon region. Cad Saude Colet 30. DOI: https://doi.org/10.1590/1414-462x202230010308
Beale J. Grabowski RC, Lokidor PL, Vercruysse K, Simms DM, 2022. Vegetation cover dynamics along two Himalayan rivers: drivers and implications of change. Sci Total Environ 849:157826. DOI: https://doi.org/10.1016/j.scitotenv.2022.157826
Brazil's Chamber of Deputies. 2021. Report shows that Brazil has not made progress on any of the UN's 169 sustainable development goals. Available from: https://www.camara.leg.br/noticias/784354-relatorio-aponta-que-o-brasil-nao-avancou-em-nenhuma-das-169-metas-de-desenvolvimento-sustentavel-da-onu/
Correa P, Oliveira Macedo C, Rocha Leão JV, 2023. Agribusiness and pesticides: two sins, one sentence in the Pará countryside. Bol Paul Geogr (Online) 1:99–121. DOI: https://doi.org/10.61636/bpg.v1i110.3006
Costa LMG, Rodrigues JC, 2022. The formation of Belém as a compact or confined city: an analysis based on forms of housing production. Geographia (Niterói) 24:a51956. DOI: https://doi.org/10.22409/GEOgraphia2022.v24i53.a51956
da Silva Prestes C, Brito de Castro J, Carvalho de Carvalho AN, Nunes Reis JT, de Castro Nunes R, Pantoja Chuva de Abreu LC, Albuquerque GDP, Santos CRC, Pires HCG, 2023. Soil and litter quality in post-mining vegetation and forest fragments in Capitão Poço, Pará, Brazil. NAT 11:58-66. DOI: https://doi.org/10.31413/nativa.v11i1.14110
De Pascali P, Bagaini A, 2019. Energy transition and urban planning for local development. A critical review of the evolution of integrated spatial and energy planning. Energies 12:35. DOI: https://doi.org/10.3390/en12010035
Furtado LG, Braga Pereira C, Silva DF, Belato LS, de Freitas Pereira BW, 2023. Detecting changes in land use and cover in the municipality of Canaã dos Carajás, Pará. Verde Grande Magazine: Geography and Interdisciplinarity 5:116–131. DOI: https://doi.org/10.46551/rvg2675239520232116131
GBD 2019 Respiratory Tract Cancers Collaborators, 2021. Global, regional, and national burden of respiratory tract cancers and associated risk factors from 1990 to 2019: a systematic analysis for the Global Burden of Disease Study 2019. Lancet Respir Med 9:1030-49.
Gu K, Li Y, Jia X, Liu C, 2023. Multiple impacts of urban built and natural environment on lung cancer incidence: a case study in Bengbu. J Healthc Eng 2023:4876404. DOI: https://doi.org/10.1155/2023/4876404
Gusmão LHA, Lobo MAA, Tourinho HLZ, 2021. Land use and land cover change and landscape haemerobics: the case of the Immediate Geographical Region of Belém - Pará (1985-2018). Geography (Londrina, Online) 30:169–89. DOI: https://doi.org/10.5433/2447-1747.2021v30n2p169
Hill W, Lim EL, Weeden CE, Lee C, Augustine M, Chen K, Kuan FC, Marongiu F, Evans EJ Jr, Moore DA, Rodrigues FS, Pich O, Bakker B, Cha H, Myers R, van Maldegem F, Boumelha J, Veeriah S, Rowan A, Naceur-Lombardelli C, Karasaki T, Sivakumar M, De S, Caswell DR, Nagano A, Black JRM, Martínez-Ruiz C, Ryu MH, Huff RD, Li S, Favé MJ, Magness A, Suárez-Bonnet A, Priestnall SL, Lüchtenborg M, Lavelle K, Pethick J, Hardy S, McRonald FE, Lin MH, Troccoli CI, Ghosh M, Miller YE, Merrick DT, Keith RL, Al Bakir M, Bailey C, Hill MS, Saal LH, Chen Y, George AM, Abbosh C, Kanu N, Lee SH, McGranahan N, Berg CD, Sasieni P, Houlston R, Turnbull C, Lam S, Awadalla P, Grönroos E, Downward J, Jacks T, Carlsten C, Malanchi I, Hackshaw A, Litchfield K; TRACERx Consortium; DeGregori J, Jamal-Hanjani M, Swanton C, 2023. Lung adenocarcinoma promotion by air pollutants. Nature 616:159-67. DOI: https://doi.org/10.1038/s41586-023-05874-3
Huang J, Deng Y, Tin MS, Lok V, Ngai CH, Zhang L, Lucero-Prisno 3rd DE, Xu W, Zheng ZJ, Elcarte E, Withers M, Wong MCS, 2022. Distribution, risk factors, and temporal trends for lung cancer incidence and mortality: a global analysis. Chest 161:1101-1111. DOI: https://doi.org/10.1016/j.chest.2021.12.655
IBGE, Brazilian Institute of Geography and Statistics. 2023. Overview of the 2022 census. Available from: https://censo2022.ibge.gov.br/panorama/index.html?localidade=BR&tema=2.
Institute for Applied Economic Research. 2015. Atlas of social vulnerability in Brazilian municipalities. Available from: https://ivs.ipea.gov.br
International Agency for Research on Cancer. 2022. Global Cancer Observatory: Cancer Today. Available from: https://gco.iarc.fr/today/enb.
Lee BXY, Hadibarata T, Yuniarto A, 2020. Phytoremediation mechanisms in air pollution control: a review. Water Air Soil Pollut 231. DOI: https://doi.org/10.1007/s11270-020-04813-6
Lim CH, Ryu J, Choi Y, Jeon SW, Lee WK, 2020. Understanding global PM2.5 concentrations and their drivers in recent decades (1998-2016). Environ Int 144:106011. DOI: https://doi.org/10.1016/j.envint.2020.106011
Mathias C, Prado GF, Mascarenhas E, Ugalde PA, Zimmer Gelatti AC, Carvalho ES, Faroni LD, Oliveira R, Lima VCC, Castro G, 2020. Lung Cancer in Brazil. J Thorac Oncol 15:170-5. DOI: https://doi.org/10.1016/j.jtho.2019.07.028
MoH. 2022. 2023 Estimate: Cancer Incidence in Brazil Available from: https://www.inca.gov.br/publicacoes/livros/estimativa-2023-incidencia-de-cancer-no-brasil
MoH. 2022. Hospital Cancer Registries (HCR). Available from: https://www.gov.br/inca/pt-br/assuntos/cancer/numeros/registros/rhc
MoH. 2024 IntegradorRHC. Hospital Cancer Registry. Available from: https://irhc.inca.gov.br/RHCNet/
Parente EB, Silva LVA, Silva WC, 2021. Deforestation in the Amazon: deforestation in view of cattle ranching expansion in the municipality of Xinguara-PA. GeoAmazônia 9:126-42.
Piedade da Silva PR, Silva EPM, Fernando EMP, 2023. The application of environmental legislation according to land use and occupation in rural properties located in the municipality of Capitão Poço in the state of Pará. Geofronter 9:1-25. DOI: https://doi.org/10.61389/geofronter.v9i1.7774
Porro R, Porro NSM, Watrin OS, Assunção HN, Santos Junior CF, 2018. Social, economic and environmental implications of a community forest management initiative in a settlement in the Eastern Amazon. Rev Econ Sociol Rural 56:623-44. DOI: https://doi.org/10.1590/1234-56781806-94790560405
Rothman KJ, Greenland S, Lash TL, 2009. Modern Epidemiology. Lippincott Williams & Wilkins, 888 pp.
Santos ERS, Teixeira BES, Almeida EC, Neves IC, Terra A, 2019. Analysing vegetation cover and surface temperature in the urban and peri-urban areas of the municipality of Santarém/PA. Geosul 34:713-738. DOI: https://doi.org/10.5007/1982-5153.2019v34n71p713
Santos MRS, Vitorino MI, Pereira LCC, Pimentel MAS, Quintão AF, 2021. Socio-environmental vulnerability to climate change: conditions in coastal municipalities in the state of Pará. Ambient soc 24. DOI: https://doi.org/10.1590/1809-4422asoc20200167r1vu2021l3ao
Silva, ACCAC, Luiz RR, Zeitoune RCG, Moraes JR, Prata-Barbosa A, Moreira JPL, 2024. T he hidden severity of the COVID-19 pandemic in children and adolescents in Brazil: a territorial analysis of hospital mortality. Cien Saude Colet 29:e02662023. DOI: https://doi.org/10.1590/1413-81232024295.02662023en
United Nations Brazil. 2024. The Sustainable Development Goals in Brazil. Health and Well-being. Available from: https://brasil.un.org/pt-br/sdgs/3.
United Nations Development Programme. 2013. Atlas of Human Development in Brazil. Available from: https://www.atlasbrasil.org.br
Wang B, Gu K, Dong D, Fang Y, Tang L, 2022. Analysis of spatial distribution of CVD and multiple environmental factors in urban residents. Comput Intell Neurosci 2022:9799054. DOI: https://doi.org/10.1155/2022/9799054
Watrin OS, Silva TM, Porro R, Oliveira Junior MM, Belluzzo AP, 2020. Dynamics of land use and cover in a Sustainable Development Project in the region of the Transamazon Highway, Pará. Soc Nat 32:92-107. DOI: https://doi.org/10.14393/SN-v32-2020-45146
Wróblewska K, Jeong BR, 2021. Effectiveness of plants and green infrastructure utilization in ambient particulate matter removal. Environ Sci Eur 33:110. DOI: https://doi.org/10.1186/s12302-021-00547-2
How to Cite
Lung cancer associated with natural vegetation cover: spatial analysis in the state of Pará, eastern Brazil. (2025). Geospatial Health, 20(2). https://doi.org/10.4081/gh.2025.1399
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